BIOMATERNITY Fertility Specialsts-Intracytoplasmic Morphologically-Selected Sperm Injection (IMSI) 1

 IMSI
Intracytoplasmic Morphologically Selected Sperm Injection

Intracytoplasmic Morphologically-Selected Sperm Injection (IMSI) technique is used during ICSI but the selection criteria of the single viable sperm to be microinjected into the egg is made through a technique called Motile Sperm Organelle Morphology Examination (MSOME) which includes the use of an ultra-high magnification microscope enhanced by digital imaging.
The use of IMSI for sperm selection significantly improves fertilization rate and embryo quality and thus the IVF outcome.

 

 

Sperm morphology has long been accepted as one of the best indicators for a positive outcome in human fertilization, whether via natural fertilization, IUI, IVF or ICSI.
More recently, IMSI, a more strict technique for selecting “normal sperm,” has been shown to improve pregnancy rates and decrease abortion rates, at least in some patient categories. is procedure, originally promoted by Bartoov and colleagues (2003), consists of real time, high magnication, motile sperm organellar morphology examination (MSOME) that uses 24 characteristics to de ne the normal morphology of seven sperm organelles: acrosome, post-acrosomal lamina, neck, mitochondria, tail, outer dense fibers and the nucleus.
MSOME is performed with an inverted light microscope equipped with high-power Nomarski optics enhanced by digital imaging that allows the embryologist to magnify sperm up to 6000 times, compared to the traditional 400 times with ICSI.
BIOMATERNITY Fertility Specialsts-Intracytoplasmic Morphologically-Selected Sperm Injection (IMSI)

IMSI: A single normal human spermatozoon showing true dimensions in μm, and a selection of dysmorphic spermatozoa. Nomarski optics at ×6000 magnification.

 

 

BIOMATERNITY Fertility Specialsts-Intracytoplasmic Morphologically-Selected Sperm Injection (IMSI) 2
BIOMATERNITY Fertility Specialsts-Intracytoplasmic Morphologically-Selected Sperm Injection (IMSI) 1

 IMSI
Intracytoplasmic Morphologically Selected Sperm Injection

Intracytoplasmic Morphologically-Selected Sperm Injection (IMSI) technique is used during ICSI but the selection criteria of the single viable sperm to be microinjected into the egg is made through a technique called Motile Sperm Organelle Morphology Examination (MSOME) which includes the use of an ultra-high magnification microscope enhanced by digital imaging.
The use of IMSI for sperm selection significantly improves fertilization rate and embryo quality and thus the IVF outcome.

 

 

BIOMATERNITY Fertility Specialsts-Intracytoplasmic Morphologically-Selected Sperm Injection (IMSI) 2

Sperm morphology has long been accepted as one of the best indicators for a positive outcome in human fertilization, whether via natural fertilization, IUI, IVF or ICSI.
More recently, IMSI, a more strict technique for selecting “normal sperm,” has been shown to improve pregnancy rates and decrease abortion rates, at least in some patient categories. is procedure, originally promoted by Bartoov and colleagues (2003), consists of real time, high magnication, motile sperm organellar morphology examination (MSOME) that uses 24 characteristics to de ne the normal morphology of seven sperm organelles: acrosome, post-acrosomal lamina, neck, mitochondria, tail, outer dense fibers and the nucleus.
MSOME is performed with an inverted light microscope equipped with high-power Nomarski optics enhanced by digital imaging that allows the embryologist to magnify sperm up to 6000 times, compared to the traditional 400 times with ICSI.
BIOMATERNITY Fertility Specialsts-Intracytoplasmic Morphologically-Selected Sperm Injection (IMSI)

IMSI: A single normal human spermatozoon showing true dimensions in μm, and a selection of dysmorphic spermatozoa. Nomarski optics at ×6000 magnification.

 

 

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