BIOMATERNITY Fertility and IVF Specialsts-FERTILITY PRESERVATION

Fertility Preservation

Egg vitrification is essential for women who wish to preserve their fertility for the future including women who want or need to delay childbearing in order to pursue educational, career or other personal goals, women with a family history of early menopause or women diagnosed with cancer.

With current advances in medicine it is possible to freeze ovarian tissue and restore fertility to those women who are receiving chemo- and/or radiotherapy for cancer, women who are diagnosed with benign ovarian tumours, those who are undergoing bone marrow transplantation, adjunctive or prophylactic oophorectomy and for women with autoimmune diseases.

Egg Social Freezing

Social egg freezing is typically offered to women under 38 years of age who want to preserve the option of having healthy, genetically related children at a later date.

Social egg freezing, followed by in vitro fertilization (IVF) and embryo transfer, offers two important benefits to women who anticipate becoming pregnant at an advanced age: it provides them with the possibility of becoming a genetic parent using their frozen–thawed eggs, and it reduces the risk of having children with chromosomal abnormalities associated with ovarian aneuploidy. In addition, for women who do not have a partner or for women who have moral concerns about the status of a developing embryo, egg freezing may be a preferable alternative to embryo freezing.

BIOMATERNITY Fertility and IVF Specialsts-EGG SOCIAL FREEZING-young professionals
BIOMATERNITY Fertility and IVF Specialsts-FERTILITY PRESERVATION

Fertility Preservation

Egg vitrification is essential for women who wish to preserve their fertility for the future including women who want or need to delay childbearing in order to pursue educational, career or other personal goals, women with a family history of early menopause or women diagnosed with cancer.

With current advances in medicine it is possible to freeze ovarian tissue and restore fertility to those women who are receiving chemo- and/or radiotherapy for cancer, women who are diagnosed with benign ovarian tumours, those who are undergoing bone marrow transplantation, adjunctive or prophylactic oophorectomy and for women with autoimmune diseases.

BIOMATERNITY Fertility and IVF Specialsts-EGG SOCIAL FREEZING-young professionals

Egg Social Freezing

Social egg freezing is typically offered to women under 38 years of age who want to preserve the option of having healthy, genetically related children at a later date.

Social egg freezing, followed by in vitro fertilization (IVF) and embryo transfer, offers two important benefits to women who anticipate becoming pregnant at an advanced age: it provides them with the possibility of becoming a genetic parent using their frozen–thawed eggs, and it reduces the risk of having children with chromosomal abnormalities associated with ovarian aneuploidy. In addition, for women who do not have a partner or for women who have moral concerns about the status of a developing embryo, egg freezing may be a preferable alternative to embryo freezing.

BIOMATERNITY Fertility Specialists

At BIOMATERNITY we understand the emotional rollercoaster your fertility journey can take you on and the dreams you have… that’s why we’re here for you every step of the way.

Fertility Preservation

Contemporary investigative efforts continue to focus on providing even more couples the opportunity to have healthy children.

One such group is women diagnosed with cancer who often sustain partial or total loss of their fertility following cancer therapy. While embryo cryopreservation prior to initiating potentially gonadotoxic treatment is the most reliable method to preserve fertility, absence of a male partner or desire not to use donor sperm often precludes this approach. In such cases, oocyte cryopreservation may provide an alternative.
Despite the fact cryopreservation of oocytes obviates the immediate need for sperm, the inability to delay initiation of chemotherapy or the presence of oestrogen sensitive malignancies precludes the use of ovarian stimulation and hence oocyte cryopreservation in many clinical scenarios.

Ovarian tissue cryopreservation, achieved by biopsying and cryopreserving ovarian cortex containing primordial follicles, followed by thawing and transplanting the autograft after completion of cancer treatment offers a potential solution in those circumstances.

Transplantation can be either orthotopic (in close proximity to the infundibulo-pelvic ligament) or heterotopic (ie, forearm or abdomen). To date, transient restoration of endocrine function has been reported with both approaches.

Embryo transfer resulting from stimulation of cryopreserved ovarian heterotopically grafted beneath the abdominal skin did not result in pregnancy. Donnez et al (2004) reported restoration of endocrine function and a live birth following orthotopic transplantation of cryopreserved ovarian tissue in a woman who became amenorrheic after being treated for Hodgkin’s lymphoma. However, some critics challenge the validity of the pregnancy arising from the cryopreserved ovarian tissue since the patient had not undergone oophorectomy. Nonetheless, these encouraging findings offer new hope to women diagnosed with cancer who desire fertility and ovarian preservation options.

Social Egg Freezing

The average age of first time motherhood has risen steadily over the last 40 years. In 2014, for the first time, the number of births to women 35 and over exceeded those to women under 25.

Many women in developed countries delay motherhood. These women can now opt to bank their oocytes for personal use later in life with the intention of increasing their chances of achieving a pregnancy after their fertility has declined. This is referred to as “social freezing”, “freezing for non-medical reasons” or freezing for “Anticipated Gamete Exhaustion (AGE)”

The correlation of increasing age with decreasing female fertility is due to the natural decline in ovarian reserve throughout all stages of a woman’s life. In addition to the decrease in number, there is a decrease in the quality of remaining oocytes.

Female fertility consistently decreases after the middle of the third decade, so oocyte cryopreservation should be done ideally earlier.

Oocyte cryopreservation has entailed important advantages for human IVF as advances in cryopreservation methodologies have dramatically improved the efficiency of oocyte cryopreservation in the last few years. Vitrification has proven to be a very useful tool for oocyte cryopreservation.

In fact, vitrification has resulted in outcomes comparable to fresh oocytes allowing women the opportunity of motherhood by saving a small number of oocytes for future utilization.

Our highly-specialized professionals at BIOMATERNITY, with the technical mastery in new technologies and medical innovations support every woman who chooses to postpone her motherhood giving her the best outcome.

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